Oral mRNA delivery using capsule-mediated gastrointestinal tissue injections
A Matter paper that screened a library of polymer mRNA nanoparticles and loaded the best ones into swallowable capsules that inject them into stomach tissue.

A Matter paper that screened a library of polymer mRNA nanoparticles and loaded the best ones into swallowable capsules that inject them into stomach tissue. In rodents and pigs the approach produced protein in several stomach cell types, pointing toward oral mRNA vaccines and therapies.



